Wednesday, 29 Nov 2023

Slimming: intestinal bacteria prevent diet

The study discovered changes in the intestinal bacteria in Obese
Over and over again to try those wanting to lose weight on a diet. However, after the Phase of resignation, the dreaded yo-yo effect. On the one hand, because many return to their old eating habits, others because bacteria in the intestine prevent a long-term effect. This was the result of an Israeli study.

The scientists from the Weizmann Institute in Israel found in their current study, that certain intestinal bacteria can be associated with frequent weight gain after dieting. The doctors published the results of their study in the journal “Nature”.

Bacteria to our previous weight remember bowel?
They belong to the people, the increase to diets fast weight? If Yes, this could hang with the bacteria in your gut. „These seem to be a kind of reminder of the past weight to behalten“, the experts speculate.

Jo-Jo effect is triggered by long-term changes in the intestinal bacteria
The current study was carried out in mice. „The results indicate that the so-called yo-Yo effect just a Foge recurring unhealthy eating habits ist“, the scientists write. This effect seems to be rather in connection with long-term changes in the intestinal bacteria, which are normally caused by Obesity.

Changes in the gut to keep extremely long
The obesity-induced changes in the intestinal micro-biome to hold about five Times as long as the actual time of the diet. This prompted the mice, after the end of the „Diät“ again, quickly increasing weight, say the scientists. If the results can be transferred to humans, this would lead to more evidence-based methods for weight loss, speculate the experts. The observed effect could explain why some people have such problems, to control your weight after a diet, the author explains Eran Elinav from the Weizmann Institute.

Study in mice under the effect of the diet sought
In the study, obese mice a high-fat were diet to a balanced diet changed. These animals were distinguished by the change in Diet in terms of its weight and a number of metabolic factors (such as, for example, the blood sugar level) of a control group of mice, say the doctors.

Obese mice retain the differences in their intestinal bacteria
The researchers found that formerly obese mice differences in your intestine keep the bacteria, which increase the weight gain of the animals by the consumption of fat rich food. If in the entrails of the control mice bacteria from the obese group were inserted, these faster weight.

Identified effect is likely to be a kind of psychological buffer
The observed effect could act as a kind of buffer against the occurring weight loss in times of food scarcity, explain the researchers. However, could lead, in the case of obesity this mechanism to a faster weight gain.

Changes in the intestinal bacteria could persist in people years
In mice, the Microbiome changed only slowly. The bacteria required for a period of six months, to return to a normal Microbiome, as in the control group. This period of time is approximately a quarter of the lifespan of a mouse in captivity, explain the scientists. The doctors projected that a comparable period of time in humans could be between months and years. This can be Concerned is a really sobering thought, says the author Elinav.

A successful change of the Mirkobioms antibiotics needed?
If the human Microbiome is subject to similar changes as the mice could be used to help the target group. As soon as the changes to the Multiple undo, it could help to keep the achieved a healthy body weight, following a diet, say the experts. The consumption of some probiotic yoghurt was not enough, however. The composition of the intestinal bacteria is difficult to change. The treatment would possibly need antibiotics to eliminate the existing bacterial Population, explain the scientists.

Intestinal bacteria from Affected seem to convert more energy into fat
The Rate of weight gain can be due to the composition of the micro biome of mice predicted, say the authors. The data suggest that a change in the metabolism of the intestinal bacteria causes the bacteria present to convert more energy into fat, the authors explain.

People with long-term obesity to take to 80 per cent, after a diet again
Other studies had previously suggested that people with long-term obesity, which lose a diet to weight, this weight, increase in 80% of cases within twelve months. (as)