Sunday, 5 Dec 2021

Seven best diagnostic criteria ID’d for childhood psoriasis

Seven best diagnostic criteria ID'd for childhood psoriasis

(HealthDay)—Seven diagnostic criteria provide good discriminatory ability for childhood psoriasis, according to a study published online Sept. 3 in the British Journal of Dermatology.

Esther Burden-The, B.M.B.S., from the University of Nottingham in the United Kingdom, and colleagues assessed the accuracy of previously agreed-upon consensus criteria for psoriasis diagnosis in children (<18 years) and developed a short list of the best predictive diagnostic criteria for childhood psoriasis.

The researchers report that for the agreed-upon consensus criteria, sensitivity was 84.4 percent, specificity was 65.1 percent, and the area under the curve (AUC) was 0.75. The best performing diagnostic criteria included the following: (1) scale and erythema in the scalp involving the hairline; (2) scaly erythema inside the external auditory meatus; (3) persistent well-demarcated erythematous rash anywhere on the body; (4) scaly erythematous plaques on the extensor surfaces of the elbows and/or knees; (5) persistent erythema in the umbilicus; (6) well-demarcated erythematous rash in the napkin area involving the crural folds; and (7) a family history of psoriasis. The prediction model showed 76.8 percent sensitivity, 72.7 percent specificity, and an AUC of 0.84 for two or more of the criteria. The c-statistic optimism adjusted shrinkage factor was 0.012.

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