Thursday, 21 Nov 2019

Sport: Doping by intestinal bacteria

Marathon runners and other top athletes to host in the intestine, a type of bacteria that increases your efficiency. In the case of unfit people, the bacteria does not occur, because these micro-organisms feed on the lactate, which is formed only with great physical effort of the muscles.

The Work started in 2015 with stool samples from runners participated in the Boston Marathon. Of them, Dr. Jonathan Sheiman, at the time, researchers in the laboratory of George Church collected samples to the Harvard Medical School, a few weeks before and after the race chair and compared them with samples from people who did not Sport. A genus of bacteria called Veillonella noticed them, which was represented in the case of marathon runners generally stronger than the Non-athletes and the Marathon is still significantly increased.

Bacteria of the genus Veillonella need to lactate in order to survive. This is produced by muscles during strenuous exercise. In the case of people who do not make an effort physically, lacks this bacteria, therefore, the food source.

In animal tests, the scientists were able to show that the training capacity enhanced in mice if they Harbor the bacteria in the gut. You also found out how this works: Veillonella metabolized lactate to propionate, which improves physical performance. As the researchers mice propionate gave by enema in the intestine, increased this assets of your Run.

The study, in the journal Nature Medicine publication, one of the first that shows such for mutually beneficial cooperation between microbes and their human host. "The host produces something that, preferably, this specific microbe. In return, the microbe creates something that the host zugutekommt", Dr. Aleksandar D. Kostic, who was involved in the work says.