Wednesday, 26 Jun 2019

Opioid safety initiative can decrease opioid prescriptions

(HealthDay)—The Opioid Safety Initiative has been effective for decreasing opioid prescriptions among patients undergoing total knee arthroplasty, according to a study published online May 30 in Anesthesiology. Qi Chen, M.D., Ph.D., from the Veterans Affairs Boston Healthcare System, and colleagues conducted an ecological study of group-level data among 700 to 850 patients undergoing total knee […]

Quality—not quantity—of sleep linked to better health in teens

With summer break and longer days ahead, parents of young teens may be wondering whether to let good sleep habits slide over the next couple of months. New research in Preventive Medicine by UBC’s Annalijn Conklin, assistant professor of pharmaceutical sciences and scientist with the Centre for Health Evaluations and Outcome Sciences, suggests there are […]

FDA says patients can take tainted blood pressure meds until shortages end

(HealthDay)—As Americans face shortages of widely used blood pressure drugs due to contamination with potentially cancer-causing impurities, the U.S. Food and Drug Administration on Thursday said patients can safely take the tainted drugs in the short term. As the agency explained, the risk of stroke and other problems from stopping the angiotensin II receptor blocker […]

FDA: Higher risk for death found with venclexta in multiple myeloma

(HealthDay)—A safety statement was issued yesterday by the U.S. Food and Drug Administration regarding risks found to be associated with the investigational use of Venclexta (venetoclax) for treatment of patients with multiple myeloma. Venclexta is currently not approved to treat multiple myeloma. The FDA conducted a review of the BELLINI clinical trial (NCT02755597, Study M14-031), […]

Is there a safer choice than opioids after a C-section?

(HealthDay)—Expectant moms often try to plan as many aspects of their upcoming delivery as they can. But one thing they might not consider is what type of pain relief they will choose if they need to have a C-section. Now, new research from the University of Texas suggests that while opioids can control pain, a […]

Trevena Announces Publication of APOLLO-1 Results in The Journal of Pain Research Highlighting Oliceridine’s Potential for Management of Moderate-to-Severe Acute Pain

March 11, 2019 — Trevena, Inc. (NASDAQ: TRVN), a biopharmaceutical company focused on the development and commercialization of innovative treatment options that target and treat diseases affecting the central nervous system, or CNS, today announced publication of APOLLO-1 (Phase 3) results in The Journal of Pain Research on the effects of oliceridine (TRV130) for management […]

Engineering treatments for the opioid epidemic

The U.S. is reeling from a public health crisis driven by the misuse of prescription and illicit opioids with nearly 12 million people abusing the drugs annually. The Midwest saw opioid overdoses increase 70 percent from July 2016 to September 2017, and every 15 minutes a baby is born suffering from opioid withdrawal as a […]

New targets for ischemic drugs

Russian scientists investigated the role of opioid receptors in protecting the heart from coronary disease: the lack of its blood supply. These receptors are mainly responsible for pain regulation. It turned out that they significantly affect the mechanism of cardioprotection. The results of the work can help to develop new drugs for ischemia. The study […]

American drug overdose death rates the highest among wealthy nations

In the most comprehensive international comparison of its kind, a USC study found that the United States has the highest drug overdose death rates among a set of high-income countries. Drug overdose mortality has reached unprecedented levels in the United States, more than tripling over the past two decades. But is this a uniquely American […]

8 Medications and Supplements To Leave Behind in 2018

Medications 1) Levofloxacin (Levaquin) Levofloxacin (Levaquin) is an antibiotic often prescribed for routine infections like bacterial sinusitis, urinary tract infections, and pneumonia, but recent warnings from the FDA should diminish levofloxacin’s popularity in 2019. Severe—and potentially permanent—side effects of levofloxacin include tendon rupture, nerve damage, dangerously low blood sugar, and mental health issues. The FDA […]

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