Thursday, 17 Oct 2019

Listening to ‘noisy knees’ to diagnose osteoarthritis: The first human cohort study

A new way of diagnosing and assessing knee osteoarthritis (OA) has moved a step closer with a major study paving the way for its use in research and clinical practice. The technique involves attaching small microphones to knees, and detecting high frequency sounds from the joint components as people perform sitting standing movements. The signals, […]

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third of patients. Based on analysis of human tissue samples, a team from the Technical University of Munich (TUM) […]

Changes associated with Alzheimer’s disease detectable in blood samples

Researchers have discovered changes in blood samples associated with Alzheimer’s disease. A new international study examined disease-discordant twin pairs: one sibling who suffered from Alzheimer’s disease and one who was cognitively healthy. The researchers used the latest genome-wide methods to find out whether the twins’ blood samples had any disease-related differences in epigenetic marks, which […]

Predictors of work disability ID’d in multiple sclerosis patients

(HealthDay)—Physical disability, depressive symptoms, and reduced information processing affect work-related disability and vocational status among patients with multiple sclerosis, according to a study published in the November issue of Multiple Sclerosis and Related Disorders. Christopher A. Povolo, from the London Health Science Center in Canada, and colleagues retrospectively reviewed the charts of 158 patients with […]

CDC: Seasonal influenza viruses circulating in southern hemisphere

(HealthDay)—Seasonal influenza viruses are circulating widely in the Southern Hemisphere, but influenza activity is currently low in the United States, according to research published in the Oct. 11 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Scott Epperson, D.V.M., from the CDC in Atlanta, and colleagues describe influenza […]

Widely used blood pressure drugs might put heart at risk

Drugs based on a molecule called dihydropyridine are commonly prescribed by doctors to treat high blood pressure and angina, a chest pain caused by reduced blood flow to the heart. However, there’s a chance that these same drugs increase the risk of sudden cardiac arrest (SCA). Because the heart stops pumping blood to the heart […]

‘Sticky’ gene may help Valium calm nerves

Between 1999 and 2017, the United States experienced a 10-fold increase in the number of people who died from overdoses of Valium and other benzodiazepines. For years, scientists thought that these powerful sedatives, which are used to treat anxiety, muscle spasms, and sleeping disorders, worked alone to calm nerves. Now, in an article published in […]

Ebola virus now squeezed into ‘corner’ of DR Congo: WHO

Credit: CC0 Public Domain Efforts to halt an Ebola epidemic in the Democratic Republic of Congo have made “significant progress”, with the virus now contained to a far smaller and mainly rural area, the World Health Organization (WHO) said Thursday. “We have put the virus in the corner,” Michael Ryan, the executive director of WHO’s […]

Prenatal stress could affect baby’s brain, say researchers

New research from King’s College London has found that maternal stress before and during pregnancy could affect a baby’s brain development. In their study published in Biological Psychiatry, MRC Doctoral Researcher in Perinatal Imaging and Health, Alexandra Lautarescu and Head of Advanced Neuroimaging, Professor Serena Counsell, for the first time looked at the relationship between […]

Navigating ‘Neuralville’: Virtual town helps map brain functions

Psychologists at Emory University have found that the human brain uses three distinct systems to perceive our environment—one for recognizing a place, another for navigating through that place and a third for navigating from one place to another. For a new paper, they designed experiments involving a simulated town and functional magnetic resonance imaging (fMRI) […]

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